Having a number of cameras ranging from Large Format, Medium Format, and smaller, I try to choose the camera that is right for the purpose. Travelling with a camera does place limits on what you can do. When travelling by car there is no real limit and on some of my trips to remote Scottish Islands I have taken the Large Format for landscape, the SLR and long lens for wildlife, then my Leica M as a carry everywhere camera.
We often go on holiday on the motorcycle and so on these occasions little cameras like the Nikon Series One the V1 are all we carry.
Quite often its the weight and size of the camera that drives what we carry.